Gene interactions and pathways from curated databases and text-mining

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BCL6 — IL8

Text-mined interactions from Literome

Nakayamada et al., Immunity 2011 : Herein, we showed interleukin-12 acting via the transcription factor STAT4 induced both Il21 and Bcl6 genes, generating cells with features of both Tfh and Th1 cells
Zhou et al., Hepatobiliary Pancreat Dis Int 2013 (Adenocarcinoma...) : The purpose of this study was to investigate the roles of the pro-apoptotic TRAIL receptors, TRAIL-R1 and TRAIL-R2, as well as Bcl-xL and TRAF2 in TRAIL induced expression of the pro-inflammatory cytokine IL-8 and the invasion promoting protein urokinase ( uPA ) in pancreatic ductal adenocarcinoma ( PDAC ) cells ... Overexpression of TRAF2 or Bcl-xL strongly increased TRAIL mediated upregulation of uPA and IL-8