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Lei et al., Amino Acids 2013
:
In contrast, cortisol and
glucagon increased leucine transamination, leucine oxidative decarboxylation, KIC production, the oxidation of leucine 2-6 carbons and the syntheses of glutamate plus
glutamine
Chang et al., Diabetes Care 2013
:
RESULTS ID
glutamine stimulated glucagon-like peptide 1 ( GLP-1 ; healthy : P < 0.05 ; T2DM : P < 0.05 ), glucose dependent insulinotropic polypeptide ( GIP ; P = 0.098 ; P < 0.05 ),
glucagon ( P < 0.01 ; P < 0.001 ), insulin ( P = 0.05 ; P < 0.01 ), and phasic pyloric pressures ( P < 0.05 ; P < 0.05 ), but did not lower blood glucose ( P = 0.077 ; P = 0.5 )
Leclercq-Meyer et al., Endocrinology 1985
:
Thus, leucine exerted a dual effect on the secretion of glucagon, the inhibitory effect of leucine prevailing at a high concentration of the branched chain amino acid and when
glucagon secretion was already
stimulated by arginine or
glutamine
Ostenson et al., Acta Endocrinol (Copenh) 1985
:
Evidence for metabolic
regulation of pancreatic
glucagon secretion by
L-glutamine ... Furthermore, the
regulation of
glucagon secretion by
glutamine appears to be reciprocally related to factors affecting glucose metabolism and ATP-levels in the A-cell
Bassett et al., J Dev Physiol 1982
:
The amino acids glycine, L-serine, L-asparagine and
L-glutamine at 5 mmol/l each markedly
increased glucagon release from perifused fetal lamb pancreas tissue, whereas the branched-chain amino acids L-leucine and L-valine had no effect
Stumvoll et al., Metabolism 1998
:
Glucagon had no effect on the renal net balance, fractional extraction, or uptake and release of either glucose or
glutamine