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SNN — TNF

Text-mined interactions from Literome

Reese et al., J Pharmacol Exp Ther 2005 : Protein kinase C epsilon regulates tumor necrosis factor-alpha induced stannin gene expression ... In this study, we investigated a signaling mechanism by which Snn gene expression is regulated by TMT and demonstrated that TNFalpha stimulates Snn gene expression in a protein kinase C epsilon dependent manner in HUVECs in response to TMT exposure ... This TNFalpha induced Snn gene expression is blocked when HUVECs were pretreated with bisindolylmaleimide I, an inhibitor of protein kinase C ( PKC ) ... Using isotype-specific siRNA against PKC, we further show that knockdown of PKC epsilon, but not PKC delta or PKC zeta, significantly blocked TNFalpha induced Snn gene expression
Billingsley et al., J Cell Biochem 2006 : TNFalpha can induce Snn mRNA expression in endothelial cells in a PKC-epsilon dependent manner
Reese et al., Gene Expr 2006 : We have recently demonstrated in human umbilical vein endothelial cells ( HUVECs ) that Snn gene expression is significantly induced by tumor necrosis factor-alpha (TNF-alpha) in a protein kinase C-epsilon ( PKC-epsilon ) -dependent manner ... In order to assess how Snn may be involved in TNF-alpha signaling in HUVEC growth arrest, we performed microarray analysis of TNF-alpha stimulated HUVECs with and without Snn knockdown via siRNA