Gene interactions and pathways from curated databases and text-mining

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LOX — PPARG

Text-mined interactions from Literome

Subbarayan et al., Neoplasia (New York, N.Y.) 2005 (Prostatic Neoplasms) : Forced expression of PPAR-gamma reduced 15-LOX-2 protein levels in normal cells, whereas forced expression of 15-LOX-2 in tumor cells suppressed PPAR-gamma protein levels
Yang et al., Cancer Gene Ther 2008 (Head and Neck Neoplasms) : The 15-LOX-2 inhibition may not be PPARgamma dependent
Hallenborg et al., Mol Cell Biol 2010 : Previously, we showed that lipoxygenase (LOX) activity is involved in activation of PPAR gamma during the early stages of adipocyte differentiation