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MMP2 — TCF4
Text-mined interactions from Literome
Rajapakse et al., Bioorg Med Chem 2007
(Fibrosarcoma) :
Further, transfection of promoter genes of MMPs and their transcription factors clearly exhibited that inhibition of
MMP-2 and MMP-9 was
due to down-regulation of
transcription factor , NF-kappaB
Zcharia et al., Anticancer Drugs 2012
(Breast Neoplasms) :
Inhibition of
matrix metalloproteinase-2 by halofuginone is
mediated by the Egr1
transcription factor
Ma et al., J Biol Chem 2013
(Osteoarthritis, Knee) :
Overexpression of
TCF4 , but not of TCF3 or LEF1,
induced MMP-1, -3, and -13 expression and generic
MMP activity in human chondrocytes
Tyagi et al., J Mol Cell Cardiol 1997
:
Results suggested that the increase in
MMP promoter activity by heparin is
due to a specific
transcription factor binding to MMP-1 promoter sequence