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CCND3 — PCNA
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PCNA
—
CCND3
(direct interaction, pull down)
Matsuoka et al., J Biol Chem 1994*
-
MIPS CORUM Cell cycle kinase complex CDK5:
Cell cycle kinase complex CDK5 complex (CCND1-CCND3-CDK5-CDKN1A-PCNA)
Zhang et al., Mol Biol Cell 1993
-
IRef Corum Interaction:
Complex of CCND1-PCNA-CCND3-CDK5-CDKN1A
(association, anti bait coimmunoprecipitation)
Zhang et al., Mol Biol Cell 1993
-
IRef Hprd Interaction:
PCNA
—
CCND3
(in vitro)
Matsuoka et al., J Biol Chem 1994*
-
IRef Ophid Interaction:
PCNA
—
CCND3
(aggregation, confirmational text mining)
Matsuoka et al., J Biol Chem 1994*
-
IRef Ophid Interaction:
PCNA
—
CCND3
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Baldassarre et al., J Clin Invest 1999
(Thyroid Neoplasms) :
In these cells,
cyclin D3
induced the formation of cytoplasmic
p27-cyclin D3-Cdk complexes, which titrated p27 away from intranuclear complexes that contain cyclins A-E and Cdk2
Boussiotis et al., Blood 2001
(Blood Group Incompatibility...) :
Moreover, these cells were incapable of clonal expansion due to defective synthesis of
cyclin D3 and cyclin A, and defective
activation of
cyclin dependent kinase (cdk)4 , cdk6, and cdk2
Liu et al., J Neurosci 2006
:
Our present study shows that c-Myc was significantly induced and that it inhibited p21 and induced proteins such as
cyclin dependent kinases,
cyclin D , and cyclin E, which are involved in the cell cycle process, along with phosphorylation of the retinoblastoma protein and Cdc2 ( cell division cycle 2 )
Lavine et al., Mol Endocrinol 2008
:
Analysis of cyclin and cdk mRNA and protein abundance revealed that CCK overexpression
increased cyclin A, cyclin B,
cyclin E, cdk1, and cdk2 with no change in cyclin D1, cyclin D2,
cyclin D3 , cdk4, or cdk6 in mouse and human islets