Gene interactions and pathways from curated databases and text-mining

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PCNA — SHH

Text-mined interactions from Literome

Heine et al., J Clin Invest 2009 : Chronic GC treatment ( from P0 through P7 ) in mouse pups inhibited Shh induced proliferation and upregulation of expression of N-myc, Gli1, and D-type cyclin protein in CGNPs. Conversely, acute GC treatment ( on P7 only ) caused transient apoptosis
Morrow et al., Arterioscler Thromb Vasc Biol 2009 : Recombinant VEGF-A increased Hrt-3 mRNA levels while siRNA knockdown abolished rShh stimulated VEGF-A expression while concomitantly inhibiting Shh induced increases in Hrt-3 mRNA levels, proliferating cell nuclear antigen ( PCNA ), and Notch 1 IC expression, respectively