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NOS2 — WNK1
Text-mined interactions from Literome
Jana et al., J Biol Chem 2001
:
Consistently, dominant negative mutants of
p65 ( Deltap65 ) and C/EBPbeta ( DeltaC/EBPbeta )
inhibited the expression of
iNOS in BV-2 microglial cells that were stimulated with the combination of IFN-gamma and CD40 ligand
Choi et al., J Pharmacol Sci 2004
:
Activations of tyrosine kinase and NFkappaB
p65 are
essential for
iNOS expression by LPS single stimulation, while TNFalpha is not a concern to iNOS expression in VSMC
Sun et al., Int Immunopharmacol 2012
(Acute Lung Injury...) :
These findings confirmed that ruscogenin significantly attenuate LPS induced acute lung injury via inhibiting expressions of TF and
iNOS and NF-?B
p65 activation , indicating it as a potential therapeutic agent for ALI or sepsis
Soares et al., J Immunol 1998
:
We report here that adenovirus mediated expression of a dominant negative C-terminal truncation mutant of
p65/RelA ( p65RHD )
inhibits the induction of proinflammatory genes, such as E-selectin, ICAM-1, VCAM-1, IL-8, and inducible
nitric oxide synthase , in EC as efficiently as does I kappaB alpha