Gene interactions and pathways from curated databases and text-mining

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NOS2 — WNK1

Text-mined interactions from Literome

Jana et al., J Biol Chem 2001 : Consistently, dominant negative mutants of p65 ( Deltap65 ) and C/EBPbeta ( DeltaC/EBPbeta ) inhibited the expression of iNOS in BV-2 microglial cells that were stimulated with the combination of IFN-gamma and CD40 ligand
Choi et al., J Pharmacol Sci 2004 : Activations of tyrosine kinase and NFkappaB p65 are essential for iNOS expression by LPS single stimulation, while TNFalpha is not a concern to iNOS expression in VSMC
Sun et al., Int Immunopharmacol 2012 (Acute Lung Injury...) : These findings confirmed that ruscogenin significantly attenuate LPS induced acute lung injury via inhibiting expressions of TF and iNOS and NF-?B p65 activation , indicating it as a potential therapeutic agent for ALI or sepsis
Soares et al., J Immunol 1998 : We report here that adenovirus mediated expression of a dominant negative C-terminal truncation mutant of p65/RelA ( p65RHD ) inhibits the induction of proinflammatory genes, such as E-selectin, ICAM-1, VCAM-1, IL-8, and inducible nitric oxide synthase , in EC as efficiently as does I kappaB alpha