Zhu et al., J Biol Chem 2007
(Bone Neoplasms...) :
Further studies reveal that EGF-like ligands strongly regulate the expression of two secreted osteoclast regulatory factors in osteoblasts by decreasing osteoprotegerin (OPG) expression and increasing monocyte chemoattractant protein 1 ( MCP1 ) expression in an EGFR dependent manner and consequently stimulate TRAP positive osteoclast formation
Yamaki et al., Exp Dermatol 2010
(Acneiform Eruptions...) :
Epidermal growth factor receptor tyrosine kinase inhibitors induce CCL2 and CCL5 via reduction in IL-1R2 in keratinocytes
Takada et al., Keio J Med 2012
(Disease Models, Animal...) :
Here, we compared and monitored the effects of EGFR inhibitors gefitinib, erlotinib and AG1517 ( PD153035 ) on the mRNA expression levels of Fosl1, Tnf and Ccl2