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EGFR — IRF1

Text-mined interactions from Literome

Andersen et al., Int J Cancer 2008 : EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells ... Ligand activated EGFR induce expression of IRF-1 via phosphorylation of STAT1 and STAT3
Rubinstein et al., FEBS Lett 1998 : Here, we report that interferon regulatory factor-1 (IRF-1) induces EGFR promoter activity up to 200-fold compared to 3-10-fold induction by other regulators ... In addition, we found that IRF-1 and tricostatin A, a deacetylase inhibitor, have a synergistic effect on EGFR promoter activity