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AHR — IL8
Text-mined interactions from Literome
Lü et al., Zhonghua Jie He He Hu Xi Za Zhi 1997
(Asthma...) :
The
IL-8 given into the airways can produce neutrophil inflammation of the airways and
induce AHR , it may play an important role in asthma, especially in the development of AHR
Qi et al., Chin Med J (Engl) 1999
(Asthma...) :
The
IL-8 could produce neutrophil inflammation of the airways and
induce AHR , which suggested that IL-8 may play an important role in asthma, especially in the development of AHR
Podechard et al., Toxicol Lett 2008
(Pneumonia) :
Such an up-regulation was likely linked to aryl hydrocarbon receptor (AhR)-activation since BP-mediated
IL-8 induction was
reduced after
AhR expression knock-down through RNA interference
Ulrich et al., Environ Sci Pollut Res Int 2010
:
Blocking of the
AhR suppressed the release of
IL-8
Tsuji et al., J Dermatol Sci 2011
(Inflammation) :
This data highlights
AhR-ROS dependent regulation of
IL-8 in NHEKs by BaP, providing a plausible explanation, at least in part, for why cigarette smoking exacerbates IL-8 related skin diseases such as psoriasis, palmoplantar pustulosis and acne
Kruber et al., Toxicology 2011
:
T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not
aryl hydrocarbon receptor dependent
interleukin-8 secretion in the human intestinal epithelial cell line Caco-2