Gene interactions and pathways from curated databases and text-mining

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FOXP3 — IL8

Text-mined interactions from Literome

Hinz et al., Cancer Res 2007 (Carcinoma...) : Down-regulation of Foxp3 with small interfering RNA ( siRNA ) in pancreatic carcinoma cells resulted in the up-regulation of interleukin 6 (IL-6) and IL-8 expression, providing evidence for a negative transcriptional activity of Foxp3 also in these epithelial cells
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo