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TLR10 — TOLLIP
Text-mined interactions from Literome
Zhang et al., J Biol Chem 2002
:
Negative
regulation of
TLR signaling by
Tollip may therefore serve to limit the production of proinflammatory mediators during inflammation and infection
Li et al., Mol Immunol 2004
:
Our study provides yet another mechanism for suppressing excessive
TLR signaling activation
mediated by
Tollip
Zhang et al., Infect Immun 2005
(Pseudomonas Infections) :
We also determined that MyD88, IRAK, TRAF6, and
Toll interacting protein (Tollip) , but not TIRAP, were involved in the
TLR mediated response to P. aeruginosa in HAECs
Hong Byun et al., J Immunol 2010
:
Interestingly, EGCG induced a rapid upregulation of
Toll interacting protein (Tollip) , a negative
regulator of
TLR signaling, and this EGCG action was prevented by 67LR silencing or anti-67LR Ab treatment
Byun et al., FEBS Lett 2011
(MAP Kinase Signaling System) :
Silencing of
Toll interacting protein (Tollip) , a negative
regulator of
TLR signaling impaired the TLR2 signaling inhibitory activity of EGCG, suggesting that TLR2 response could be inhibited by EGCG via 67LR and Tollip
Byun et al., Biochem Biophys Res Commun 2013
:
Quercetin markedly elevated the expression of the
Toll interacting protein , a negative
regulator of
TLR signaling