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CCR1 — CSF2
Text-mined interactions from Literome
Cheng et al., J Immunol 2001
(Calcium Signaling) :
In this study, the
effect of
GM-CSF , a well characterized PMN priming and maturation factor, on
CC-chemokine receptor ( CCR ) expression in PMN was investigated ...
GM-CSF induced up-regulation of
CCR1 showed functional consequences because GM-CSF treated PMN, but not control cells, responded to the CC chemokines macrophage inflammatory protein-1alpha, monocyte chemoattractant protein-3, and RANTES in assays of chemotactic migration and intracellular calcium mobilization
Li et al., Biochem Biophys Res Commun 2003
:
IL-10 synergistically enhances
GM-CSF induced
CCR1 expression in myelomonocytic cells ... IL-10 augmented
GM-CSF induced
CCR1 protein expression with no effect on mRNA expression ... Our findings indicate that IL-10 may potentiate
GM-CSF induced
CCR1 protein expression in U937 cells via activation of PKB/Akt and p70 ( S6k )
Poppensieker et al., Proc Natl Acad Sci U S A 2012
(Encephalomyelitis, Autoimmune, Experimental...) :
Thus,
CCR4 dependent
GM-CSF production in DCs required for IL-23 release in these cells is a major component in the development of EAE