Gene interactions and pathways from curated databases and text-mining

◀ Back to CCR1

CCR1 — CSF2

Text-mined interactions from Literome

Cheng et al., J Immunol 2001 (Calcium Signaling) : In this study, the effect of GM-CSF , a well characterized PMN priming and maturation factor, on CC-chemokine receptor ( CCR ) expression in PMN was investigated ... GM-CSF induced up-regulation of CCR1 showed functional consequences because GM-CSF treated PMN, but not control cells, responded to the CC chemokines macrophage inflammatory protein-1alpha, monocyte chemoattractant protein-3, and RANTES in assays of chemotactic migration and intracellular calcium mobilization
Li et al., Biochem Biophys Res Commun 2003 : IL-10 synergistically enhances GM-CSF induced CCR1 expression in myelomonocytic cells ... IL-10 augmented GM-CSF induced CCR1 protein expression with no effect on mRNA expression ... Our findings indicate that IL-10 may potentiate GM-CSF induced CCR1 protein expression in U937 cells via activation of PKB/Akt and p70 ( S6k )
Poppensieker et al., Proc Natl Acad Sci U S A 2012 (Encephalomyelitis, Autoimmune, Experimental...) : Thus, CCR4 dependent GM-CSF production in DCs required for IL-23 release in these cells is a major component in the development of EAE