Gene interactions and pathways from curated databases and text-mining

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BCL2 — TNFSF13

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: BCL2 → TNFSF13 (increases)
    Evidence: expression of BAFF and APRIL receptors (B-cell maturation antigen [BCMA], transmembrane activator and calcium modulator and cyclophilin ligand interactor [TACI], and BAFF-R) in a majority of 13 myeloma cell lines and in the purified primary myeloma cells of 11 patients. APRIL and BAFF were potent survival factors for exogenous cytokine-dependent myeloma cell lines and were autocrine growth factors for the RPMI8226 and L363 autonomously growing cell lines. These factors activated nuclear factor (...