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CASP4 — SETD2
Text-mined interactions from Literome
Kannan et al., Am J Physiol Gastrointest Liver Physiol 2011
(Acute Lung Injury...) :
Specifically, partial
HIF-1a deficiency
attenuated SMAO induced increases in intestinal permeability, lipid peroxidation, mucosal
caspase-3 activity, and IL-1ß mRNA levels
Harasawa et al., Acta histochemica et cytochemica 2011
:
As a result, it was suggested that everolimus administration would be helpful as an anti-tumor therapy for CCA not only via down-regulation of p-mTOR but also degradation of
HIF-1a by VHL and
induction of apoptosis by cleaved
caspase-3
Huang et al., Asian Pac J Cancer Prev 2012
(Burkitt Lymphoma) :
Western blot assay revealed increase in expression of
caspase-3 , 8 and 9 with prolongation of transfection ( P < 0.05 ). Following hypoxia treatment, mRNA expression of HIF-1a remained unchanged in three groups ( P > 0.05 ) but the protein expression of
HIF-1a markedly
increased ( P < 0.05 )