Gene interactions and pathways from curated databases and text-mining

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CNP — TGFB1

Text-mined interactions from Literome

Woodard et al., Am J Physiol Regul Integr Comp Physiol 2002 : The production and secretion of CNP in vascular smooth muscle cells is stimulated by transforming growth factor-beta , whereas basic fibroblast growth factor plays an inhibitory role
Horio et al., Endocrinology 2003 : TGF-beta1 , basic fibroblast growth factor, and endothelin-1 significantly stimulated CNP secretion
Suga et al., J Clin Invest 1992 : In addition, transforming growth factor ( TGF ) -beta , one of the key growth factors for vascular remodeling, markedly stimulated the expression of CNPmRNA and induced a tremendous increase in CNP secretion
Hagiwara et al., J Biol Chem 1994 : In addition, TGF-beta 1 , a multifunctional cytokine, induced a marked increase in CNP secretion and CNP mRNA levels in chondrocytes
Hagiwara et al., J Biochem 1996 : We had proposed previously that C-type natriuretic peptide (CNP) might be a potent antimitogenic factor for chondrocytes, and TGF-beta 1 induced a marked increase in CNP secretion of chondrocytes ... These results suggest that the expression of CNP and NPR-B might be involved in in vitro dedifferentiation of chondrocytes and TGF-beta 1 does not affect the increasing level of CNP during in vitro dedifferentiation