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CNP — TGFB1
Text-mined interactions from Literome
Woodard et al., Am J Physiol Regul Integr Comp Physiol 2002
:
The production and secretion of
CNP in vascular smooth muscle cells is
stimulated by
transforming growth factor-beta , whereas basic fibroblast growth factor plays an inhibitory role
Horio et al., Endocrinology 2003
:
TGF-beta1 , basic fibroblast growth factor, and endothelin-1 significantly
stimulated CNP secretion
Suga et al., J Clin Invest 1992
:
In addition,
transforming growth factor ( TGF ) -beta , one of the key growth factors for vascular remodeling, markedly stimulated the expression of CNPmRNA and
induced a tremendous increase in
CNP secretion
Hagiwara et al., J Biol Chem 1994
:
In addition,
TGF-beta 1 , a multifunctional cytokine,
induced a marked increase in CNP secretion and
CNP mRNA levels in chondrocytes
Hagiwara et al., J Biochem 1996
:
We had proposed previously that C-type natriuretic peptide (CNP) might be a potent antimitogenic factor for chondrocytes, and
TGF-beta 1 induced a marked increase in
CNP secretion of chondrocytes ... These results suggest that the expression of CNP and NPR-B might be involved in in vitro dedifferentiation of chondrocytes and
TGF-beta 1 does not
affect the increasing level of
CNP during in vitro dedifferentiation