Gene interactions and pathways from curated databases and text-mining

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CYP11A1 — JUN

Text-mined interactions from Literome

Pestell et al., J Biol Chem 1995 : Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage ( CYP11A1 ) promoter
Pestell et al., Mol Endocrinol 1996 (Choriocarcinoma) : Overexpression of c-Jun induced the CYP11A1 promoter through the EGF-RE ; however, c-Ets-2 activation of the CYP11A1 promoter ( 12-fold ) required the proximal ras-responsive promoter sequences that are distinct from the EGF/MEK/c-Jun-responsive element