Schultess et al., Blood 2005
:
The Ras-like guanine-nucleotide binding protein Rap1 controls integrin alpha ( IIb ) beta3 activity and platelet aggregation
Danielewski et al., Thromb Haemost 2005
(Calcium Signaling) :
Since Rap1 controls the function of integrin alpha ( IIb ) beta3, we propose that Rap 1 inhibition might play a central role in the anti-aggregatory actions of NO/cGMP