Gene interactions and pathways from curated databases and text-mining

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FGF1 — RAC1

Text-mined interactions from Literome

Chotani et al., J Biol Chem 2000 : The small GTPases Ras, Rac , and Cdc42 transcriptionally regulate expression of human fibroblast growth factor 1
Park et al., J Neurochem 2007 : Transient transfection of kinase-inactive MEKK7 or chemical inhibitors of JNK significantly decreased the activation of Rac1 by FGF
Elfenbein et al., J Cell Biol 2009 : Thus, FGF2 induced Rac1 activation depends on the suppression of RhoG by a previously uncharacterized ternary S4-synectin-RhoGDI1 protein complex and activation via PKCalpha