We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to GRAP2

GNRH1 — GRAP2

Text-mined interactions from Literome

Liu et al., Mol Endocrinol 2002 : In this paper, we demonstrate that GnRH activates ERK, c-Jun N-terminal kinase, and p38MAPK in the LbetaT2 gonadotrope cell line
Bonfil et al., Endocrinology 2004 : Extracellular signal regulated kinase, Jun N-terminal kinase, p38 , and c-Src are involved in gonadotropin releasing hormone stimulated activity of the glycoprotein hormone follicle stimulating hormone beta-subunit promoter ... Thus, PKC, ERK, JNK, p38 , and c-Src, but not Ca ( 2+ ), are involved in GnRH induction of the ovine FSHbeta gene
White et al., Mol Endocrinol 2008 (MAP Kinase Signaling System) : In contrast to Galpha ( i ) or chimeric Galpha ( qi5 ), transfection of Galpha ( q ) cDNA enabled GnRH to induce phosphorylation of ERK, jun-N-terminal kinase, and P38
Sviridonov et al., Mol Cell Endocrinol 2013 (MAP Kinase Signaling System...) : Sustained activation of p38 was observed for PMA and A23187 in Du-145 cells, while p38 activation by GnRH , PMA and A23187 in LßT2 cells was transient