◀ Back to IL10

IL10 — MYD88

Text-mined interactions from Literome

Oshikawa et al., Biochem Biophys Res Commun 2003 (Lung Diseases) : The results demonstrated three patterns of gene expression : the TLR2 and myeloid differentiation factor 88 ( MyD88 ) gene expressions were induced in AM in response to lipopolysaccharide (LPS), interleukin (IL)-1beta , or tumor necrosis factor-alpha or in the lung tissue of an LPS induced acute lung injury model ; the gene expressions of TLR1, -3, -6, CD14, and MD2 were unchanged ; and the TLR4 and TLR5 gene expressions were downregulated in AM following inflammatory stimuli
Boonstra et al., J Immunol 2006 : Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF dependent TLR signals, and TLR independent signals
Csóka et al., Blood 2007 : The stimulatory effect of adenosine on E coli induced IL-10 production did not require toll-like receptor 4 (TLR4) or MyD88 , but was blocked by p38 inhibition
Rad et al., Gastroenterology 2007 (Gastritis...) : The adaptor protein Myd88 mediates Toll-like receptor ( TLR ), interleukin (IL)-1 , and IL-18 signaling
Leichtle et al., BMC immunology 2009 (Otitis Media) : Activated TLRs signal via two alternative intracellular signaling molecules with differing effects ; MyD88 ( Myeloid differentiation primary response gene 88 ) inducing primarily interleukin expression and TRIF ( Tir-domain containing adaptor inducing interferon beta ) mediating type I interferon ( IFN ) expression
Kissner et al., Innate Immun 2011 (Disease Models, Animal...) : Our results indicated that elevated tumor necrosis factor-a, interferon-?, interleukin (IL)-1a/ß and IL-6 production from mouse spleen cells treated with SEB alone or in combination with lipopolysaccharide (LPS) was regulated by MyD88
Bosschaerts et al., PLoS Pathog 2010 (Trypanosomiasis) : Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling
Bankoti et al., J Immunol 2012 (Leishmaniasis, Visceral) : B cells were able to capture parasites, which was associated with upregulation of surface IgM and MyD88 dependent IL-10 production
Klaas et al., J Immunol 2012 : This was accompanied by a strong reduction in MyD88 dependent secretion of TNF-a, IL-6, IL-12, and IL-10
Koike et al., Immunol Lett 2012 (Pancreatitis) : MyD88 dependent interleukin-10 production from regulatory CD11b ( + ) Gr-1 ( high ) cells suppresses development of acute cerulein pancreatitis in mice
Bagchi et al., Cytokine 2013 : Interleukin-10 activates Toll-like receptor 4 and requires MyD88 for cardiomyocyte survival ... IL-10 caused a significant increase in the expression of CD14, MyD88 and TLR4