Gene interactions and pathways from curated databases and text-mining

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ARSK — POLDIP2

Text-mined interactions from Literome

Matsuzawa et al., Nat Immunol 2005 (MAP Kinase Signaling System...) : Here we used ASK1-deficient mice to show that ASK1 was selectively required for lipopolysaccharide induced activation of p38 but not of Jnk or the transcription factor NF-kappaB
Tran et al., J Biol Chem 2012 (MAP Kinase Signaling System) : In agreement with this, overexpression of ASK1 or TAK1 resulted in enhanced p38MAPK activation, and their knockdown inhibited p38MAPK in C2C12 cells