Gene interactions and pathways from curated databases and text-mining

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CCR6 — CD4

Text-mined interactions from Literome

Ravindran et al., Proc Natl Acad Sci U S A 2007 (Inflammation...) : Furthermore, lymph node pathogen-specific CD4 T cell activation required CCR6 and cell migration from the site of infection
Rivino et al., J Exp Med 2010 : Human CD4 ( + ) CCR6 ( + ) memory T cells contained comparable numbers of IL-17- and IL-10 producing cells, and CCR6 was induced under both Th17 promoting conditions and upon tolerogenic T cell priming with transforming growth factor ( TGF ) -beta
Nakamoto et al., Gastroenterology 2012 (Disease Models, Animal...) : Under inflammatory conditions, CCR9 ( + ) macrophages induced naive CD4 ( + ) T cells to become interferon gamma producing Th1 cells in vivo and in vitro
Kim et al., PloS one 2013 : Curcumin not merely blocks, but regulates CD2/CD3/CD28 initiated CD4 ( + ) T cell activation by augmenting CD69, CCR7 , L-selectin and TGF-ß1 expression followed by regulatory T cell generation