Gene interactions and pathways from curated databases and text-mining

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CD83 — IRF6

Text-mined interactions from Literome

Brodskyn et al., Infect Immun 2002 : LPS induced HLA-DR, CD83 , and CD86 up-regulation was significantly inhibited by GIPL
Weigt et al., Immunobiology 2003 : MALP-2 and LPS stimulation induced the expression of CD83 and increased the expressions of CD80, CD86, HLA-ABC and CD40
Giordano et al., J Immunol 2003 : Treatment during DC differentiation with either cAMP or cGMP analogues hampered LPS induced expression of CD83 , DC-LAMP, and CCR7 and the ability of DCs to migrate toward CCL19/macrophage-inflammatory protein 3beta
Cohen et al., J Dent Res 2004 (Periodontal Diseases) : Pre-treatment with glucocorticoids ( GC ) and interleukin-10 (IL-10) abolished the effect of Pg.LPS on CD80, CD83 , and CD86, and on CCL3 and CCL5 production
Chen et al., J Immunol 2004 : PS liposomes inhibited the up-regulation of HLA-ABC, HLA-DR, CD80, CD86, CD40, and CD83 , as well as the production of IL-12p70 by human DCs in response to LPS
Nakahara et al., Int Immunol 2004 : SP600125, a specific inhibitor of JNK, inhibited the LPS induced up-regulation of CD80, CD83 , CD86 and CD54, but augmented the up-regulation of HLA-DR. SP600125 slightly inhibited the down-regulation of FITC-dextran uptake during DC maturation
Dudziak et al., J Immunol 2005 : Stimulation of PBMCs with PHA, TNF-alpha, or LPS leads to the up-regulation of the full-length CD83 transcript and to a strong down-regulation of two of the three smaller transcripts
Mahanonda et al., Asian Pac J Allergy Immunol 2006 : Unlike Escherichia coli and A. actinomycetemcomitans LPS, P. gingivalis LPS induced only low levels of CD40, CD80, HLA-DR and CD83 expression on Mo-DCs
Messmer et al., Mol Med 2006 (Opioid-Related Disorders) : Chronic morphine treatment ( 10 ( -8 ) to 10 ( -12 ) M ) during the development of DCs from monocytes augmented LPS induced upregulation of HLA-DR, CD86, CD80, and CD83 and increased the T cell stimulatory capacity of DCs, which could be inhibited by naloxone, an opioid receptor antagonist
Jiang et al., J Immunol 2007 : NGF could markedly promote LPS induced expression of HLA-DR, CD40, CD80, CD83 , CD86, CCR7, secretion of IL-12p40 and proinflammatory cytokines IL-1, IL-6, TNF-alpha, and the T cell stimulating capacity of MoDCs, indicating that NGF can promote LPS induced DC maturation
Santander et al., Biomedica 2007 (Chagas Disease) : KMP-1 1 protein does not affect the maturation of dendritic cells, but in the presence of LPS the K1 peptide leads to a decreased expression of CD86 and CD83 as well as interleukin-12 production, This phenomenon may be associated with an impaired T cell stimulation
Michielsen et al., PloS one 2011 (Colorectal Neoplasms) : Pre-treatment of monocyte derived dendritic cells with this tumour conditioned media inhibited the up-regulation of CD86, CD83 , CD54 and HLA-DR in response to LPS , enhancing IL-10 while reducing IL-12p70 secretion
Michielsen et al., Mol Cancer Ther 2012 (Colorectal Neoplasms) : Inhibition of LPS induced CD1d ( P = 0.021, HR = 1.096 ) and CD83 ( P = 0.017, HR = 1.083 ) by TCM and inhibition of CD1d ( P = 0.017, HR = 1.067 ), CD83 ( P = 0.032, HR = 1.035 ), and IL-12p70 ( P = 0.037, HR = 1.036 ) by BCM was associated with poor survival in colorectal cancer patients
Salamone et al., Hum Reprod 2012 (Neovascularization, Pathologic) : Trophoblast cells significantly prevented the increase in CD83 expression induced by LPS without affecting the expression of CD86, CD40 and human leukocyte antigen-DR ( P < 0.05 )
Stein et al., Mol Cell Biol 2013 : Multiple interferon regulatory factor and NF-?B sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells
Chen et al., Clin Dev Immunol 2013 : Moreover, the inhibition of LPS induced MAPK activation and NF- ? B translocation may contribute to the suppressive effect of DXM on BMDCs. Remarkably, DXM decreased the LPS induced surface expression of CD80, CD83 , and HLA-DR and the secretion of IL-6 and IL-12 in human monocyte derived dendritic cells ( MDDCs )
Rieser et al., Blood 1998 : In addition, the LPS induced expression of the CD83 maturation antigen was inhibited in these cells