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CAPN10 — PARP1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Sohn et al., Cancer Lett 2003
(Carcinoma, Hepatocellular...) :
TG-induced apoptosis was assessed by morphological changes, DNA fragmentation, cleavages of poly ( ADP-ribose ) polymerase (
PARP ), and
activation of
calpain and caspase-12
Vosler et al., Exp Neurol 2009
:
Both calpain and
PARP-1 are involved with AIF processing as AIF truncation, nuclear translocation and neuronal death were
attenuated by
calpain inhibition using adeno associated virus mediated overexpression of the endogenous calpain inhibitor, calpastatin, or treatment with the PARP-1 inhibitor 3-ABA ... Activation of
PARP-1 is
necessary for
calpain activation as PARP-1 inhibition blocked mitochondrial calpain activation