UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PDGFB

PDGFB — SLC9A3R2

Pathways - manually collected, often from reviews:

NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer)/NHERF1-2 complex (PDGFRB-SLC9A3R1_SLC9A3R2-PDGFB) → PDGF-BB/PDGFRB (dimer) complex (PDGFRB-PDGFB) (modification, collaborate)
Maudsley et al., Mol Cell Biol 2000, Demoulin et al., Biochem J 2003 *, James et al., J Cell Sci 2004, Theisen et al., Mol Biol Cell 2007 *
Evidence: physical interaction
NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer)/NHERF1-2 complex (PDGFRB-SLC9A3R1_SLC9A3R2-PDGFB) → NHERF1-2 (SLC9A3R1/SLC9A3R2) (modification, collaborate)
Maudsley et al., Mol Cell Biol 2000, Demoulin et al., Biochem J 2003 *, James et al., J Cell Sci 2004, Theisen et al., Mol Biol Cell 2007 *
Evidence: physical interaction
NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer) complex (PDGFRB-PDGFB) → NHERF1-2 (SLC9A3R1/SLC9A3R2) (modification, collaborate)
Maudsley et al., Mol Cell Biol 2000, Demoulin et al., Biochem J 2003 *, James et al., J Cell Sci 2004, Theisen et al., Mol Biol Cell 2007 *
Evidence: physical interaction
NCI Pathway Database PDGFR-beta signaling pathway: None → PDGF-BB/PDGFRB (dimer)/NHERF1-2/PTEN complex (PDGFRB-SLC9A3R1_SLC9A3R2-PTEN-PDGFB) (modification, collaborate)
Takahashi et al., EMBO J 2006, Maehama et al., J Biol Chem 1998 *
Evidence: assay
NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer)/NHERF1-2 complex (PDGFRB-SLC9A3R1_SLC9A3R2-PDGFB) → PDGF-BB/PDGFRB (dimer)/NHERF1-2/PTEN complex (PDGFRB-SLC9A3R1_SLC9A3R2-PTEN-PDGFB) (modification, collaborate)
Takahashi et al., EMBO J 2006
Evidence: assay, physical interaction
NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer)/NHERF1-2 complex (PDGFRB-SLC9A3R1_SLC9A3R2-PDGFB) → PTEN (PTEN) (modification, collaborate) Takahashi et al., EMBO J 2006
Evidence: assay, physical interaction
NCI Pathway Database PDGFR-beta signaling pathway: PDGF-BB/PDGFRB (dimer)/NHERF1-2/PTEN complex (PDGFRB-SLC9A3R1_SLC9A3R2-PTEN-PDGFB) → PTEN (PTEN) (modification, collaborate) Takahashi et al., EMBO J 2006
Evidence: assay, physical interaction