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Zhang et al., Acta Pharmacol Sin 2005
(Hypertension, Pulmonary) :
The up-regulation of eNOS and iNOS mRNA levels induced by MCT was significantly reversed in 3 CPU 86017 groups, and preproET-1 mRNA abundance was also reduced notably in CPU 86017 80 mg/kg-1/d-1 group vs the PAH group
Homma et al., Respiration 2006
(Hypertension, Pulmonary...) :
Genistein supplementation improved MCT induced downregulation of expression of endothelial nitric oxide synthase in the lungs