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CCR5 — STAT3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: STAT3 — CCR5 (physical association, affinity chromatography technology) Mellado et al., EMBO J 2001*
• IRef Hprd Interaction: STAT3 — CCR5 (in vivo) Shahrara et al., Arthritis Rheum 2003*

Text-mined interactions from Literome

Wong et al., J Biol Chem 2001 : Previously we reported that in T cells, RANTES activation of CCR5 results in Stat1 and Stat3 phosphorylation-activation, leading to Stat1 : 1 and Stat1 : 3 dimers that exhibit DNA binding activity and the transcriptional induction of a Stat-inducible gene, c-fos
Makuta et al., Biol Pharm Bull 2003 : These results first indicate that Erk1/2 and STAT-3 regulate CCR5 expression, and that Erk mediated phosphorylation of Ser is required for full stimulation of STAT-3 in CCR5 expression