Gene interactions and pathways from curated databases and text-mining

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REN — TP53

Text-mined interactions from Literome

Leri et al., Circ Res 1999 : Moreover, activation of p53 upregulates the cellular renin-angiotensin system (RAS)
Leri et al., Am J Pathol 2000 : Inhibition of p53 function prevents renin-angiotensin system activation and stretch mediated myocyte apoptosis
Pierzchalski et al., Exp Cell Res 1997 : Thus, p53 enhances the myocyte renin-angiotensin-system and decreases the Bcl-2/Bax ratio in the cells, triggering apoptosis