Gene interactions and pathways from curated databases and text-mining

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CFTR — NFKBIA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Boncoeur et al., Am J Pathol 2008 : In this study, we evaluated the role of CFTR in the control of ubiquitin-proteasome activity and nuclear factor (NF)-kappaB/IkappaB-alpha signaling after lung oxidative stress
Xu et al., PloS one 2010 : Reduction of CFTR expression in AM resulted in increased secretion of IL-8, increased phosphorylation of NF-kappaB, a positive regulator of IL-8 expression, and decreased expression of IkappaB-alpha , the inhibitory protein of NF-kappaB activation