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CFTR — PLA2G4A

Text-mined interactions from Literome

Borot et al., PloS one 2009 : These results show that ( i ) CFTR may form a complex with cPLA2alpha and ANXA1 via interaction with p11, ( ii ) CFTR inhibition and DRM disruption induce eicosanoid synthesis, and ( iii ) suggest that the putative cPLA2/ANXA1/p11/CFTR complex may participate in the modulation of the TNF-alpha induced production of eicosanoids, pointing to the importance of membrane composition and CFTR function in the regulation of inflammation mediator synthesis
Berguerand et al., Am J Respir Cell Mol Biol 1997 (Cystic Fibrosis) : Hence normal CFTR , or normally processed deltaF508 CFTR, inhibit cPLA2 stimulation