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CFTR — SGK1

Text-mined interactions from Literome

Wagner et al., Cell Physiol Biochem 2001 (Cystic Fibrosis) : Effects of the serine/threonine kinase SGK1 on the epithelial Na ( + ) channel ( ENaC ) and CFTR : implications for cystic fibrosis ... Here we further examined the effects of SGK1 on ENaC and CFTR which have mutual interactions and we analyzed sgk1 mRNA abundance in lung tissue from CF patients
Shaw et al., Cell Physiol Biochem 2008 : Since SGK1 has been shown to increase the plasma membrane abundance of CFTR in Xenopus oocytes, these observations suggest that acute adaptation ( hours ) to increased salinity in killifish involves translocation of CFTR from an intracellular pool to the plasma membrane, and that this effect may be mediated by SGK1
Gehring et al., Biochem Biophys Res Commun 2009 : CFTR is stimulated by the serum and glucocorticoid-inducible kinase SGK1
Notch et al., PloS one 2011 : To test the hypothesis that SGK1 mediates the increase in plasma membrane CFTR we designed two functionally different vivo-morpholinos to knock down SGK1 in gill, and developed and validated a vivo-morpholino knock down technique for adult killifish