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CFTR — SULT1E1

Text-mined interactions from Literome

He et al., Biochim Biophys Acta 2008 (Carcinoma, Hepatocellular...) : Repression of CFTR activity in human MMNK-1 cholangiocytes induces sulfotransferase 1E1 expression in co-cultured HepG2 hepatocytes ... Results demonstrate that inhibition of CFTR expression in MMNK-1 cells results in the induction of SULT1E1 message and activity in HepG2 cells in the Transwell system
Falany et al., J Steroid Biochem Mol Biol 2009 (Cystic Fibrosis...) : To investigate the mechanism by which the absence of CFTR in human cholangiocytes induces SULT1E1 expression in hepatocytes, a membrane separated human MMNK-1 cholangiocyte and human HepG2 hepatocyte co-culture system was developed ... Thus, the loss of CFTR activity in cholangiocytes stimulates the expression of SULT1E1 in hepatocytes by a paracrine mechanism