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IRF6 — TNFSF10

Text-mined interactions from Literome

Halaas et al., Scand J Immunol 2000 : Flow cytometric analysis showed low surface and high intracellular levels of APO2L , and LPS increased the expression of both ... LPS also stimulated the release of soluble APO2L from the monocytes and macrophages
Ehrlich et al., Cytokine 2003 : In particular, not only PHA+IL-2 but also LPS were able to induce secretion of soluble TRAIL, but did not enhance the expression of surface bound TRAIL
Halaas et al., Scand J Immunol 2004 : LPS also prevented release of TRAIL from GBS stimulated monocytes
Zheng et al., Zhonghua Gan Zang Bing Za Zhi 2005 (Carcinoma, Hepatocellular...) : LPS only slightly increased membrane bound TRAIL expression of macrophages ... On the other hand, soluble TRAIL in the supernatant was increased with LPS stimulation, and the optimal concentration of LPS was 100 ng/ml ( sTRAIL value 67.40 ng/ml+/-5.08 ng/ml ) ... LPS increases the expression of soluble TRAIL in macrophages, and soluble TRAIL is toxic to HepG2 cells
Tsuno et al., J Immunother 2009 (Adenocarcinoma...) : In IFN-alpha treated OVCAR3 cells, IRF9-RNAi inhibited transcription of TRAIL whereas Stat1-RNAi did not, suggesting that the transcription of TRAIL induced by IFN-alpha predominantly required IRF9
Cho et al., Immunology 2010 : TRAIL expression was strongly induced in DCs upon stimulation with lipopolysaccharide (LPS) or Polyinosine-polycytidylic acid ( poly ( I:C ) ) stimulation