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MYLIP — RPTOR

Text-mined interactions from Literome

Nagaraja et al., Mol Endocrinol 2010 (Adenocarcinoma, Clear Cell...) : Overexpression of mir-100 inhibited mTOR signaling and enhanced sensitivity to the rapamycin analog RAD001 ( everolimus ), confirming the key relationship between mir-100 and the mTOR pathway
Wu et al., Proc Natl Acad Sci U S A 2012 : However, excessive miR-17-92 expression enhances mammalian target of rapamycin (mTOR) signaling and strongly skews the differentiation toward short lived terminal effector cells
Jin et al., PloS one 2013 : We further demonstrated that miR-99 family members regulate cell proliferation, cell migration, and AKT/mTOR signaling ... Combined experimental and bioinformatics analyses revealed that miR-99 family members regulate AKT/mTOR signaling by targeting multiple genes, including known target genes ( e.g., IGF1R, mTOR ) and a new target ( AKT1 )