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MAPK6 — MOS
Text-mined interactions from Literome
Howard et al., Mol Cell Biol 1999
:
Moreover, inhibition of
MAPK signaling
blocked progesterone induced
Mos protein accumulation
Chau et al., Biol Cell 1998
:
Mos induced p42
mitogen activated protein kinase activation stabilizes M-phase in Xenopus egg extracts after cyclin destruction
Kim et al., Cell Growth Differ 2000
:
Expression of Nm23 proteins delayed the accumulation of Mos and the activation of p42 mitogen activated protein kinase ( MAPK ) in progesterone treated oocytes but had no discernible effect on
Mos induced p42
MAPK activation
Verlhac et al., EMBO J 2000
:
Thus
Mos activates
MAPK through two opposite pathways : activation of MEK1 and inhibition of a phosphatase
Kajiura-Kobayashi et al., Dev Genes Evol 2000
(MAP Kinase Signaling System) :
The function of
Mos is
mediated by
MAP kinase ( MAPK )
Russo et al., HFSP journal 2009
:
After activation of the cascade,
Mos activity is
stabilized by
MAPK via a feedback loop
Gotoh et al., J Biol Chem 1995
:
The increase in
Mos protein and the
activation of
MAPK by injecting cyclin A protein into immature oocytes were both blocked also by cycloheximide treatment
Chen et al., Mol Cell Biol 1995
:
In Xenopus oocytes,
Mos synthesis is
required for progesterone induced activation of
MAPK and maturation promoting factor
Choi et al., Proc Natl Acad Sci U S A 1996
:
Mos is an upstream
activator of
mitogen activated protein kinase ( MAPK ) and, in mouse oocytes, is responsible for metaphase II arrest
Araki et al., Biol Reprod 1996
:
In Xenopus oocytes,
Mos activates the mitogen activated protein kinase (
MAPK ) signal transduction cascade and regulates meiosis ... In the present study, we used c-mos knockout mouse oocytes and examined the roles of Mos in mouse oocyte maturation and fertilization, including whether
Mos controls
MAPK and maturation promoting factor ( MPF ) activity
Sagata et al., Bioessays 1997
(Cell Transformation, Neoplastic) :
In both of these cell types,
Mos activates
mitogen activated protein kinase ( MAPK ), which seems largely to mediate its different functions in both oocyte maturation and cellular transformation
Chen et al., Proc Natl Acad Sci U S A 1997
:
We have previously shown that the binding of CKIIbeta to
Mos represses Mos mediated
mitogen activated protein kinase ( MAPK ) activation and that the ectopic expression of CKIIbeta inhibits progesterone induced Xenopus oocyte maturation