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ITIH4 — TP53

Text-mined interactions from Literome

Garden et al., FASEB J 2004 (AIDS Dementia Complex...) : Using neuron/microglia co-culture of mixed p53 genotype, we observed that both neurons and microglia require p53 for gp120 induced neuronal apoptosis ... Taken together these findings demonstrate a novel role for p53 in the microglial response to gp120
Khan et al., Mol Cell Neurosci 2005 : Inhibition of CXCR 4 by AMD 3100 abrogates the effect of gp120 on both p53 and Apaf-1
Yeung et al., AIDS 1998 (Neuroblastoma) : RT-PCR and Western blot analyses revealed that the gp120 mediated induction of apoptosis was dependent on a gp120 induced and gp120 sustained upregulation of p53 ... The induction of p53 by gp120 was specific, since an antibody against gp120 prevented both the induction of p53 and subsequent apoptosis in SK-N-SH cells