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CCR5 — IL16
Text-mined interactions from Literome
Mashikian et al., J Immunol 1999
:
Reciprocal desensitization of
CCR5 and CD4 is
mediated by
IL-16 and macrophage-inflammatory protein-1 beta, respectively
Biasin et al., J Infect Dis 2000
:
However,
interleukin (IL)-6 , IL-10, IL-12, interferon (IFN)-gamma, and tumor necrosis factor (TNF)-alpha and -beta mRNA were elevated in PBMC and cervical mucosa biopsy specimens of ESN and HIV infected women ;
CCR5 and CXCR4 mRNA were
augmented in cervical mucosa biopsy specimens, but not in PBMC, of ESN and HIV infected women ; HIV-specific IFN-gamma secreting cells were detected in vaginal washes of ESN and HIV infected women ; and phenotypic alterations were present in PBMC of ESN women
Wang et al., Biochem Biophys Res Commun 2003
:
R5-tropic HIV-1 glycoprotein 120, but not
interleukin-16 , the natural agonist, or X4-tropic glycoprotein 120,
inhibited MIP-1beta binding to
CCR5 in the presence of monomeric and dimeric soluble CD4
Zhang et al., Arthritis Rheum 2005
(Arthritis, Rheumatoid) :
In contrast,
interleukin-12 stimulation
induced the up-regulation of
CCR5 and a shift in the in vivo homing pattern away from the lymph nodes toward the inflamed synovium