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MET — TNF
Text-mined interactions from Literome
Goldstein et al., Curr Med Res Opin 2006
(Cardiovascular Diseases...) :
RSG +
MET reduced C-reactive protein ( CRP ; -23.9 % ; 95 % CI : -40.4 to -2.8 ), plasminogen activator inhibitor-1 ( PAI-1 ) activity ( -30.1 % ; 95 % CI : -44.5 to -11.9 ), PAI-1 antigen ( -15.5 % ; 95 % CI : -28.3 to -0.3 ) and matrix metalloproteinase-9 ( MMP-9 ; -13.8 % ; 95 % CI : -25.1 to -0.9 ), but
increased tumor necrosis factor-alpha ( TNF-alpha ; 27.0 % ; 95 % CI : 6.8 to 50.9 )
Dai et al., J Cell Biochem 2009
:
Previously, we showed that
Met gene expression is
regulated by
TNF alpha ... In p65-/- mouse embryonic fibroblasts ( MEFs ),
Met induction by
TNF alpha is abrogated while Met 's basal gene expression is reduced by half as compared to controls
Kawasaki et al., Cytotechnology 2010
:
In the presence of
TNF-alpha ,
Met and Cys significantly
increased the LPL activity, and Met also enhanced the LPL mRNA level
Zhong et al., Zhongguo Yao Li Xue Bao 1996
:
Met-enk promoted NK activity at 1 x 10 ( -8 ) - 1 x 10 ( -5 ) mol.L-1,
increased TNF-alpha production both in vitro and in vivo, and enhanced IL-12 p35 gene transcription after ip 0.1 mg.kg-1 for 6 d