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IRF6 — PTHLH

Text-mined interactions from Literome

Funk et al., Endocrinology 1994 : IL-4, a prototypical antiinflammatory cytokine, also had a paradoxical effect on LPS induction of splenic PTHrP mRNA levels ... Instead of inhibiting LPS induction of splenic PTHrP mRNA levels in OuJ or HeJ mice, IL-4 ( 200 ng ) actually stimulated PTHrP mRNA levels
Funk et al., J Clin Invest 1993 : Since endotoxin ( LPS ) causes many of its effects indirectly by inducing cytokines, studies were undertaken to determine whether LPS might also induce splenic PTHrP expression ... Anti-TNF antibody blocked LPS induction of splenic PTHrP mRNA in C3H/OuJ mice by 68 %, indicating that TNF is a mediator of the LPS induction of PTHrP levels