Suzuki et al., Antioxid Redox Signal 1999
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We investigated the interrelationship of these elements in NIH/3T3 fibroblasts and found that Ang II induces GATA4 activity and Hcy alters Ang II signaling
Hautala et al., Pflugers Arch 2002
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These results show that ET-1 and Ang II are required for the stimulation of GATA4 and AP-1 DNA binding activity in response to direct left ventricular wall stretch
Tang et al., Biochem Pharmacol 2011
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Together, these results indicate that binding of GATA4 to DNA is increased by Ang II via extracellular signal regulated protein kinase 1/2 ( ERK 1/2 ) and p38 kinase, which increases FGF2 gene expression in neonatal rat cardiomyocytes