◀ Back to IL10
ELAVL1 — IL10
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
ELAVL1
→
IL10
(decreases)
Evidence: One manuscript describes the downregulation of HuR by IL-10 in monocytes [67], and attributes this as a major mechanism whereby IL-10 exerts systemic anti-inflammatory effects.
Text-mined interactions from Literome
Rajasingh et al., FASEB J 2006
(Carotid Artery Injuries) :
IL-10 induced TNF-alpha mRNA destabilization is mediated via
IL-10 suppression of p38 MAP kinase activation and
inhibition of
HuR expression ... IL-10 sensitivity to TNF depends on the ability of
IL-10 to
inhibit the expression and mRNA stabilizing protein
HuR and via IL-10 mediated repression of p38 mitogen activated protein ( MAP ) kinase activation
Krishnamurthy et al., Circ Res 2009
(Disease Models, Animal...) :
These changes were associated with
IL-10 mediated inhibition of p38 mitogen activated protein kinase activation and repression of the cytokine mRNA stabilizing protein
HuR