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NGF — TLR4

Text-mined interactions from Literome

Jiang et al., Mol Immunol 2008 : However, there was no such effect on DCs derived from TLR4-deficient mice, indicating the LPS induced upregulation of NGF and p75 ( NTR ) was TLR4 pathway dependent ... Thus, TLR4 signaling can induce expression of NGF and p75 ( NTR ) on DCs via activation of p38 MAPK and NF-kappaB pathways, suggesting that NGF may be involved in the pathogenesis of inflammatory diseases
Micera et al., Molecular vision 2009 (Conjunctivitis, Allergic) : The different NGF induced TLR response between VKC and healthy-control conjunctival ECs as well as the different cytokine response might reflect a different pattern of cell activation according to the state of VKC