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IRF6 — MAP2K1
Text-mined interactions from Literome
Dumitru et al., Cell 2000
(MAP Kinase Signaling System...) :
LPS stimulation of peritoneal macrophages from these mice did not
activate MEK1 , ERK1, and ERK2 but did activate JNK, p38 MAPK, and NF-kappaB
Stollenwerk et al., Atherosclerosis 2005
(Arteriosclerosis...) :
VLDL activated mitogen activated protein kinase-ERK kinase 1/2 ( MEK1/2 ), and potentiated
LPS induced
MEK1/2 activation
Minami et al., J Biol Chem 2008
(Atherosclerosis) :
Similarly, directed EPRAP expression in RAW264.7 cells suppresses
LPS induced p105 phosphorylation and degradation, and subsequent activation of
mitogen activated protein kinase kinase 1/2
Tsai et al., Inflammation 2008
:
Furthermore, ATRA suppressed the expression of
LPS stimulated c-Raf,
MKK1/2 and ERK expression of THP-1 cells
Geppert et al., Mol Med 1994
:
In RAW 264.7 mouse macrophages, both ERK2 and
MEK1 activity are
induced by
LPS treatment