Gene interactions and pathways from curated databases and text-mining

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EPHB2 — LAT

Text-mined interactions from Literome

Zhang et al., Int Immunol 1999 : LAT is also required for Erk activation, CD69 up-regulation, and AP- and NFAT mediated gene transcription
Kremer et al., J Immunol 2003 : Because TCR activates ERK via SLP-76 mediated activation of the linker of activated T cells (LAT) scaffold protein, we examined the role of LAT in SDF-1alpha mediated ERK activation
Dorn et al., Blood 2007 : Although RhoH is not required for TCR induced activation of ZAP70 and ZAP70 mediated activation of p38, it is crucial for the tyrosine phosphorylation of LAT , PLCgamma1, and Vav1 and for the activation of Erk and calcium influx
Liu et al., J Leukoc Biol 2007 : In addition, ZAP-70 mediated pathways, such as the association of linker for activation of T cells with PLCgamma and activation of ERK , were also intact in the presence of ( S ) -armepavine
Kovalovsky et al., J Immunol 2009 : TCR activation in double positive cells with stabilized beta-catenin triggered signaling associated with negative selection, including sustained overactivation of Lat and Jnk and a transient activation of Erk