Gene interactions and pathways from curated databases and text-mining

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SP1 — UGCG

Text-mined interactions from Literome

Uchida et al., Cancer Res 2004 : Because we reported that a GC-rich/Sp1 promoter binding region was of importance in the regulation of GCS expression, the role of Sp1 in DOX induced up-regulation of GCS and apoptosis was investigated
Liu et al., FASEB J 2008 (Adenocarcinoma...) : Promoter truncation, point mutation, gel-shift, and protein-DNA ELISA analysis showed that transcription factor Sp1 was essential for ceramide induced GCS up-regulation