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IL13 — MMP3

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Oriente et al., J Pharmacol Exp Ther 2000 : Finally, IL-13 inhibited IL-1beta induced matrix metalloproteinase (MMP)-1 and MMP-3 production and enhanced tissue inhibitor of metalloproteinase ( TIMP ) -1 generation from NF ; although similar effects were observed with IL-4, TGF-beta(1) transiently enhanced MMP-1 and MMP-3 generation without effecting TIMP-1 ... In KF, IL-13 and IL-4 inhibited MMP-3 , whereas TGF-beta(1) enhanced MMP-3 ; TIMP-1 was unaffected by any of the three cytokines
Cleaver et al., Ann Rheum Dis 2001 : Northern blot analyses were performed to determine the effects of IL13 on the induction of matrix metalloproteinase-1 (MMP-1), MMP-3 , MMP-13, and TIMP-1 gene expression ... Northern blot analysis showed that IL13 down regulated MMP-3 and MMP-13 levels but up regulated MMP-1 and TIMP-1 gene expression in bovine nasal chondrocytes at 24 hours
Bamba et al., J Gastroenterol 2003 : Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts : role of interleukin-17
Fleenor et al., Invest Ophthalmol Vis Sci 2003 : In the trabecular meshwork ( TM ), interleukin (IL)-1alpha is a potent inducer of MMP-3 expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Ma et al., J Immunol 2004 (Inflammation) : C10/CCL6 neutralization also decreased the ability of IL-13 to stimulate the production of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha, MMP-2 , MMP-9, and cathepsins-K, -L, and -S and the ability of IL-13 to inhibit alpha1-antitrypsin
Borghaei et al., Biochem Biophys Res Commun 2004 : A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting induction of MMP-3 transcription by interleukin 1 ; and the 6T allele has been associated with decreased expression of MMP-3 as compared to the 5T allele
Inoue et al., Rheumatol Int 2005 (Osteoarthritis, Hip...) : Induction of vascular endothelial growth factor and matrix metalloproteinase-3 ( stromelysin ) by interleukin-1 in human articular chondrocytes and synoviocytes
Nabbe et al., Arthritis Res Ther 2005 (Arthritis, Experimental...) : In contrast, mRNA levels of MMP-3 , -9, -12, and -13 were significantly higher and IL-1 protein, which induces production of latent MMPs, was increased fivefold by IL-13
Fukuda et al., Invest Ophthalmol Vis Sci 2006 : IL-4 and -13 each inhibit MMP-3 synthesis in human conjunctival fibroblasts, suggesting that these Th2 cytokines may contribute to the excessive deposition of ECM in giant papillae by preventing matrix degradation mediated by this enzyme
Stewart et al., BMC molecular biology 2007 : Interleukin-4 inhibition of interleukin-1 induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts
Chang et al., Rheumatol Int 2007 (Chondrosarcoma) : Activin A suppresses interleukin-1 induced matrix metalloproteinase 3 secretion in human chondrosarcoma cells
Purwar et al., J Invest Dermatol 2008 (Dermatitis...) : IL-13 stimulation of KCs induced the expression of MMP-9 but not of MMP-3 or MMP-2 at mRNA level
Madala et al., J Immunol 2010 (Fibrosis...) : Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like MMP12, MMP13 expression was highly dependent on IL-13 and type II-IL-4 receptor signaling
Wang et al., J Biol Chem 2010 : Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1 induced matrix metalloproteinase-3 expression
Saw et al., Am J Pathol 2011 (Fibrosis...) : Differences between pemphigoid and normal conjunctival fibroblasts with respect to collagen contraction and MMP secretion in the presence of interleukin-13 were also observed
Fujisawa et al., Int J Cancer 2012 (Neoplasm Invasiveness...) : Mechanistically, IL-13 enhanced ERK1/2, AP-1 and MMP activities only in IL-13Ra2 positive cells but not in IL-13Ra2 negative cells
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts