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AKT2 — SLC9A1

Text-mined interactions from Literome

Cechin et al., Neurochem Res 2005 (Glioma) : Inhibition of Rho kinase or NHE1 did not reduce the LPA induced phosphorylation of ERK, Akt or CREB
Bourguignon et al., Semin Cancer Biol 2008 (Neoplasms) : A special focus is placed on the role of HA-mediated CD44 interaction with unique downstream effectors ( e.g., the cytoskeletal protein, ankyrin and/or various GTPases ( e.g., RhoA, Rac1 and Cdc42 ) ) in coordinating intracellular signaling pathways ( e.g., Ca ( 2+ ) mobilization, Rho signaling, PI3 kinase-AKT activation , NHE1 mediated cellular acidification, transcriptional upregulation and cytoskeletal function ) and generating the concomitant onset of tumor cell activities ( e.g., tumor cell adhesion, growth, survival, migration and invasion ) and tumor progression
Shah et al., Am J Physiol Heart Circ Physiol 2010 : These results suggest that 1 ) ANG- ( 1-7 ) increased ANP secretion at high atrial pacing via the Mas/PI3K/Akt pathway and the activation of Na(+)/H(+) exchanger-1 and CaMKII and 2 ) ANG- ( 1-7 ) decreased cardiac hypertrophy which might be mediated by ANP
Clement et al., J Cell Sci 2013 (MAP Kinase Signaling System) : We here show that AKT and MEK1/2-ERK1/2-p90 ( RSK ) inhibition reduced PDGF-AA induced cell migration by distinct mechanisms : AKT inhibition reduced NHE1 activity by blocking the translocation of NHE1 to the cell membrane