Gene interactions and pathways from curated databases and text-mining

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PI3 — SMAD2

Text-mined interactions from Literome

Lee et al., Biochem Biophys Res Commun 2004 : In addition, PI3K inhibitor, dominant negative Akt, and dominant negative ILK could not block TGFbeta mediated C-terminal phosphorylation of Smad2
Park et al., J Invest Dermatol 2008 (Keloid) : The level of Smad2/3 , signal transducer and activator of transcription-3 ( STAT3 ), and p38 phosphorylation is more enhanced in KFs, and EGCG inhibited phosphorylation of phosphatidylinositol-3-kinase (PI3K) , extracellular signal regulated protein kinase 1/2 ( ERK1/2 ), and STAT3 ( Tyr705 and Ser727 )